"[Mr. Quammen] is not just among our best science writers but among our best writers, period." —Dwight Garner, New York Times The next big human pandemic—the next disease cataclysm, perhaps on the scale of AIDS or the 1918 influenza—is likely to be caused by a new virus coming to humans from wildlife. Experts call such an event “spillover” and they warn us to brace ourselves. David Quammen has tracked this subject from the jungles of Central Africa, the rooftops of Bangladesh, and the caves of southern China to the laboratories where researchers work in space suits to study lethal viruses. He illuminates the dynamics of Ebola, SARS, bird flu, Lyme disease, and other emerging threats and tells the story of AIDS and its origins as it has never before been told. Spillover reads like a mystery tale, full of mayhem and clues and questions. When the Next Big One arrives, what will it look like? From which innocent host animal will it emerge? Will we be ready?

Author David Quammen
Isbn 0393239225
Genre Science
Year 2012-10-01
Pages 592
Language English
File format PDF

“A frightening and fascinating masterpiece of science reporting that reads like a detective story.” —Walter Isaacson In 1976 a deadly virus emerged from the Congo forest. As swiftly as it came, it disappeared, leaving no trace. Over the four decades since, Ebola has emerged sporadically, each time to devastating effect. It can kill up to 90 percent of its victims. In between these outbreaks, it is untraceable, hiding deep in the jungle. The search is on to find Ebola’s elusive host animal. And until we find it, Ebola will continue to strike. Acclaimed science writer and explorer David Quammen first came near the virus while he was traveling in the jungles of Gabon, accompanied by local men whose village had been devastated by a recent outbreak. Here he tells the story of Ebola—its past, present, and its unknowable future. Extracted from Spillover by David Quammen, updated and with additional material.

Author David Quammen
Isbn 0393351564
Genre Science
Year 2014-10-20
Pages 128
Language English
File format PDF

Dynamic young Stanford biologist Nathan Wolfe reveals the surprising origins of the world's most deadly viruses, and how we can overcome catastrophic pandemics. In The Viral Storm, award-winning biologist Nathan Wolfe tells the story of how viruses and human beings have evolved side by side through history; how deadly viruses like HIV, swine flu, and bird flu almost wiped us out in the past; and why modern life has made our species vulnerable to the threat of a global pandemic. Wolfe's research missions to the jungles of Africa and the rain forests of Borneo have earned him the nickname "the Indiana Jones of virus hunters," and here Wolfe takes readers along on his groundbreaking and often dangerous research trips—to reveal the surprising origins of the most deadly diseases and to explain the role that viruses have played in human evolution. In a world where each new outbreak seems worse than the one before, Wolfe points the way forward, as new technologies are brought to bear in the most remote areas of the world to neutralize these viruses and even harness their power for the good of humanity. His provocative vision of the future will change the way we think about viruses, and perhaps remove a potential threat to humanity's survival.

Author Nathan Wolfe
Isbn 1429973595
Genre Science
Year 2011-10-11
Pages 320
Language English
File format PDF

In this "frightening and fascinating masterpiece" (Walter Isaacson), David Quammen explores the true origins of HIV/AIDS. The real story of AIDS—how it originated with a virus in a chimpanzee, jumped to one human, and then infected more than 60 million people—is very different from what most of us think we know. Recent research has revealed dark surprises and yielded a radically new scenario of how AIDS began and spread. Excerpted and adapted from the book Spillover, with a new introduction by the author, Quammen's hair-raising investigation tracks the virus from chimp populations in the jungles of southeastern Cameroon to laboratories across the globe, as he unravels the mysteries of when, where, and under what circumstances such a consequential "spillover" can happen. An audacious search for answers amid more than a century of data, The Chimp and the River tells the haunting tale of one of the most devastating pandemics of our time.

Author David Quammen
Isbn 0393350851
Genre Science
Year 2015-02-16
Pages 144
Language English
File format PDF

Finalist for the Los Angeles Times Book Prize | A New York Times Editor's Choice “[A] grounded, bracingly intelligent study” —Nature Prizewinning science journalist Sonia Shah presents a startling examination of the pandemics that have ravaged humanity—and shows us how history can prepare us to confront the most serious acute global health emergency of our time. Over the past fifty years, more than three hundred infectious diseases have either emerged or reemerged, appearing in places where they’ve never before been seen. Years before the sudden arrival of COVID-19, ninety percent of epidemiologists predicted that one of them would cause a deadly pandemic sometime in the next two generations. It might be Ebola, avian flu, a drug-resistant superbug, or something completely new, like the novel virus the world is confronting today. While it was impossible to predict the emergence of SARS-CoV-2—and it remains impossible to predict which pathogen will cause the next global outbreak—by unraveling the stories of pandemics past we can begin to better understand our own future, and to prepare for what it holds in store. In Pandemic: Tracking Contagions, from Cholera to Ebola and Beyond, Sonia Shah interweaves history, original reportage, and personal narrative to explore the origins of epidemics, drawing parallels between cholera—one of history’s most deadly and disruptive pandemic-causing pathogens—and the new diseases that stalk humankind today. She tracks each stage of cholera’s dramatic journey, from its emergence in the South Asian hinterlands as a harmless microbe to its rapid dispersal across the nineteenth-century world, all the way to its latest beachhead in Haiti. Along the way she reports on the pathogens now following in cholera’s footsteps, from the MRSA bacterium that besieges her own family to the never-before-seen killers coming out of China’s wet markets, the surgical wards of New Delhi, and the suburban backyards of the East Coast. Delving into the convoluted science, strange politics, and checkered history of one of the world’s deadliest diseases, Pandemic is a work of epidemiological history like no other, with urgent lessons for our own time. “Shah proves a disquieting Virgil, guiding us through the hells ruled by [infectious diseases] . . . the power of Shah's account lies in her ability to track simultaneously the multiple dimensions of the public-health crises we are facing.” —The Chicago Tribune

Author Sonia Shah
Isbn 0374708746
Genre Medical
Year 2016-02-16
Pages 288
Language English
File format PDF

The ultimate guide for anyone wondering how President Joe Biden will respond to the COVID-19 pandemic—all his plans, goals, and executive orders in response to the coronavirus crisis. Shortly after being inaugurated as the 46th President of the United States, Joe Biden and his administration released this 200 page guide detailing his plans to respond to the coronavirus pandemic. The National Strategy for the COVID-19 Response and Pandemic Preparedness breaks down seven crucial goals of President Joe Biden's administration with regards to the coronavirus pandemic: 1. Restore trust with the American people. 2. Mount a safe, effective, and comprehensive vaccination campaign. 3. Mitigate spread through expanding masking, testing, data, treatments, health care workforce, and clear public health standards. 4. Immediately expand emergency relief and exercise the Defense Production Act. 5. Safely reopen schools, businesses, and travel while protecting workers. 6. Protect those most at risk and advance equity, including across racial, ethnic and rural/urban lines. 7. Restore U.S. leadership globally and build better preparedness for future threats. Each of these goals are explained and detailed in the book, with evidence about the current circumstances and how we got here, as well as plans and concrete steps to achieve each goal. Also included is the full text of the many Executive Orders that will be issued by President Biden to achieve each of these goals. The National Strategy for the COVID-19 Response and Pandemic Preparedness is required reading for anyone interested in or concerned about the COVID-19 pandemic and its effects on American society.

Author Joseph R. Biden, Jr.
Isbn 1510767614
Genre Political Science
Year 2021-05-18
Pages 208
Language English
File format PDF

In this New York Times bestseller and longlist nominee for the National Book Award, “our greatest living chronicler of the natural world” (The New York Times), David Quammen explains how recent discoveries in molecular biology affect our understanding of evolution and life’s history. In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field—the study of life’s diversity and relatedness at the molecular level—is horizontal gene transfer (HGT), or the movement of genes across species lines. It turns out that HGT has been widespread and important; we now know that roughly eight percent of the human genome arrived sideways by viral infection—a type of HGT. In The Tangled Tree, “the grandest tale in biology….David Quammen presents the science—and the scientists involved—with patience, candor, and flair” (Nature). We learn about the major players, such as Carl Woese, the most important little-known biologist of the twentieth century; Lynn Margulis, the notorious maverick whose wild ideas about “mosaic” creatures proved to be true; and Tsutomu Wantanabe, who discovered that the scourge of antibiotic-resistant bacteria is a direct result of horizontal gene transfer, bringing the deep study of genome histories to bear on a global crisis in public health. “David Quammen proves to be an immensely well-informed guide to a complex story” (The Wall Street Journal). In The Tangled Tree, he explains how molecular studies of evolution have brought startling recognitions about the tangled tree of life—including where we humans fit upon it. Thanks to new technologies, we now have the ability to alter even our genetic composition—through sideways insertions, as nature has long been doing. “The Tangled Tree is a source of wonder….Quammen has written a deep and daring intellectual adventure” (The Boston Globe).

Author David Quammen
Isbn 1476776644
Genre Science
Year 2018-08-14
Pages 480
Language English
File format PDF

In Wild Thoughts from Wild Places, award-winning journalist David Quammen reminds us why he has become one of our most beloved science and nature writers. This collection of twenty-three of Quammen's most intriguing, most exciting, most memorable pieces takes us to meet kayakers on the Futaleufu River of southern Chile, where Quammen describes how it feels to travel in fast company and flail for survival in the river's maw. We are introduced to the commerce in pearls (and black-market parrots) in the Aru Islands of eastern Indonesia. Quammen even finds wildness in smog-choked Los Angeles -- embodied in an elusive population of urban coyotes, too stubborn and too clever to surrender to the sprawl of civilization. With humor and intelligence, David Quammen's Wild Thoughts from Wild Places also reminds us that humans are just one of the many species on earth with motivations, goals, quirks, and eccentricities. Expect to be entertained and moved on this journey through the wilds of science and nature.

Author David Quammen
Isbn 1439125279
Genre Nature
Year 2012-10-16
Pages 304
Language English
File format PDF

In the past half century, deadly disease outbreaks caused by novel viruses of animal origin - Nipah virus in Malaysia, Hendra virus in Australia, Hantavirus in the United States, Ebola virus in Africa, along with HIV (human immunodeficiency virus), several influenza subtypes, and the SARS (sudden acute respiratory syndrome) and MERS (Middle East respiratory syndrome) coronaviruses - have underscored the urgency of understanding factors influencing viral disease emergence and spread. Emerging Viral Diseases is the summary of a public workshop hosted in March 2014 to examine factors driving the appearance, establishment, and spread of emerging, re-emerging and novel viral diseases; the global health and economic impacts of recently emerging and novel viral diseases in humans; and the scientific and policy approaches to improving domestic and international capacity to detect and respond to global outbreaks of infectious disease. This report is a record of the presentations and discussion of the event.

Author Institute of Medicine,Board on Global Health,Forum on Microbial Threats
Isbn 0309314003
Genre Medical
Year 2015-03-19
Pages 336
Language English
File format PDF

#1 New York Times bestseller “Barry will teach you almost everything you need to know about one of the deadliest outbreaks in human history.”—Bill Gates "Monumental... an authoritative and disturbing morality tale."—Chicago Tribune The strongest weapon against pandemic is the truth. Read why in the definitive account of the 1918 Flu Epidemic. Magisterial in its breadth of perspective and depth of research, The Great Influenza provides us with a precise and sobering model as we confront the epidemics looming on our own horizon. As Barry concludes, "The final lesson of 1918, a simple one yet one most difficult to execute, is that...those in authority must retain the public's trust. The way to do that is to distort nothing, to put the best face on nothing, to try to manipulate no one. Lincoln said that first, and best. A leader must make whatever horror exists concrete. Only then will people be able to break it apart." At the height of World War I, history’s most lethal influenza virus erupted in an army camp in Kansas, moved east with American troops, then exploded, killing as many as 100 million people worldwide. It killed more people in twenty-four months than AIDS killed in twenty-four years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision of science and epidemic disease.

Author John M. Barry
Isbn 1101200979
Genre History
Year 2005-10-04
Pages 560
Language English
File format PDF

Emerging infectious diseases are often due to environmental disruption, which exposes microbes to a different niche that selects for new virulence traits and facilitates transmission between animals and humans. Thus, health of humans also depends upon health of animals and the environment – a concept called One Health. This book presents core concepts, compelling evidence, successful applications, and remaining challenges of One Health approaches to thwarting the threat of emerging infectious disease. Written by scientists working in the field, this book will provide a series of "stories" about how disruption of the environment and transmission from animal hosts is responsible for emerging human and animal diseases. Explains the concept of One Health and the history of the One Health paradigm shift. Traces the emergence of devastating new diseases in both animals and humans. Presents case histories of notable, new zoonoses, including West Nile virus, hantavirus, Lyme disease, SARS, and salmonella. Links several epidemic zoonoses with the environmental factors that promote them. Offers insight into the mechanisms of microbial evolution toward pathogenicity. Discusses the many causes behind the emergence of antibiotic resistance. Presents new technologies and approaches for public health disease surveillance. Offers political and bureaucratic strategies for promoting the global acceptance of One Health.

Author Ronald M. Atlas,Stanley Maloy
Isbn 1555818439
Genre Medical
Year 2020-07-24
Pages 331
Language English
File format PDF

Approximately 75% of emerging infectious diseases are zoonoses, and the rate of emergence of zoonotic diseases is on the rise. Bats are being increasingly recognised as an important reservoir of zoonotic viruses of different families, including SARS coronavirus, Nipah virus, Hendra virus and Ebola virus. Understanding bats’ role in emerging zoonotic diseases is crucial to this rapidly expanding area of research. Bats and Viruses: A New Frontier of Emerging Infectious Diseases provides an updated overview of research focusing on bat biology and the role bats play as hosts of many major zoonotic viruses. The text covers bat biology, immunology, and genomics. Chapters also delve into the various major bat-borne virus families, including lyssaviruses, paramyxoviruses, coronaviruses, filoviruses and reoviruses, among others. Edited by leaders in the field, Bats and Viruses: A New Frontier of Emerging Infectious Diseases is a timely, invaluable reference for bat researchers studying microbiology, virology and immunology, as well as infectious disease workers and epidemiologists, among others.

Author Lin-Fa Wang,Christopher Cowled
Isbn 1118818725
Genre Science
Year 2015-06-29
Pages 384
Language English
File format PDF

"David Quammen is simply the best natural essayist working today."--Tim Cahill, author of Lost in My Own Backyard "Lively writing about science and nature depends less on the offering of good answers, I think, than on the offering of good questions," said David Quammen in the original introduction to Natural Acts. For more than two decades, he has stuck to that credo. In this updated version of curiosity leads him from New Mexico to Romania, from the Congo to the Amazon, asking questions about mosquitoes (what are their redeeming merits?), dinosaurs (how did they change the life of a dyslexic Vietnam vet?), and cloning (can it save endangered species?). This revised and expanded edition best-loved "Natural Acts" columns, which first appeared in Outside magazine in the early 1980s, and includes recent pieces such as "Planet of Weeds," an influential new Natural Acts is an eye-opening journey that will please both Quammen fans and newcomers to his work. Song lyrics have been redacted from this ebook owing to permissions issues.

Author David Quammen
Isbn 0393076326
Genre Nature
Year 2009-03-30
Pages 352
Language English
File format PDF

“Jonathan Quick offers a compelling and intensely readable plan to prevent worldwide infectious outbreaks. The End of Epidemics is essential reading for those who might be affected by a future pandemic—that is, just about everyone.”—Sandeep Jauhar, bestselling author of Heart: A History The 2020 outbreak of coronavirus has terrified the world--and revealed how unprepared we are for the next outbreak of an infectious disease. Somewhere in nature, a killer virus is boiling up in the bloodstream of a bird, bat, monkey, or pig, preparing to jump to a human being. This not-yet-detected germ has the potential to wipe out millions of lives over a matter of weeks or months. That risk makes the threat posed by ISIS, a ground war, a massive climate event, or even the dropping of a nuclear bomb on a major city pale in comparison. In The End of Epidemics, Duke Global Health Institute faculty member and past Chair of the Global Health Council Dr. Jonathan D. Quick examines the eradication of smallpox and devastating effects of influenza, AIDS, SARS, Ebola, and other viral diseases . Analyzing local and global efforts to contain these diseases and citing firsthand accounts of failure and success, Dr. Quick proposes a new set of actions which he has coined "The Power of Seven," to end epidemics before they can begin. These actions include: - Spending prudently to prevent disease before an epidemic strikes, rather than spending too little, too late - Ensuring prompt, open, and accurate communication between nations and aid agencies, instead of secrecy and territorial disputes - Fighting disease and preventing panic with innovation and good science Practical and urgent, The End of Epidemics is crucial reading for citizens, health professionals, and policy makers alike. “Dr. Quick’s urgent message makes one hope that this book will reach a huge audience and that its exhortations will be acted on everywhere.”—The Wall Street Journal

Author Dr. Jonathan D. Quick,Bronwyn Fryer
Isbn 125011778X
Genre Medical
Year 2018-01-30
Pages 288
Language English
File format PDF

Get on the fast track to understanding neuroscience Investigating how your senses work, how you move, and how you think and feel, Neuroscience For Dummies, 2nd Edition is your straight-forward guide to the most complicated structure known in the universe: the brain. Covering the most recent scientific discoveries and complemented with helpful diagrams and engaging anecdotes that help bring the information to life, this updated edition offers a compelling and plain-English look at how the brain and nervous system function. Simply put, the human brain is an endlessly fascinating subject: it holds the secrets to your personality, use of language, memories, and the way your body operates. In just the past few years alone, exciting new technologies and an explosion of knowledge have transformed the field of neuroscience—and this friendly guide is here to serve as your roadmap to the latest findings and research. Packed with new content on genetics and epigenetics and increased coverage of hippocampus and depression, this new edition of Neuroscience For Dummies is an eye-opening and fascinating read for readers of all walks of life. Covers how gender affects brain function Illustrates why some people are more sensitive to pain than others Explains what constitutes intelligence and its different levels Offers guidance on improving your learning What is the biological basis of consciousness? How are mental illnesses related to changes in brain function? Find the answers to these and countless other questions in Neuroscience For Dummies, 2nd Edition

Author Frank Amthor
Isbn 1119224918
Genre Medical
Year 2016-04-14
Pages 408
Language English
File format PDF

A National Bestseller, a New York Times Notable Book, and an Entertainment Weekly Best Book of the Year from the author of Unexpected Life “By turns a medical thriller, detective story, and paean to city life, Johnson's account of the outbreak and its modern implications is a true page-turner.” —The Washington Post “Thought-provoking.” —Entertainment Weekly It's the summer of 1854, and London is just emerging as one of the first modern cities in the world. But lacking the infrastructure-garbage removal, clean water, sewers-necessary to support its rapidly expanding population, the city has become the perfect breeding ground for a terrifying disease no one knows how to cure. As the cholera outbreak takes hold, a physician and a local curate are spurred to action-and ultimately solve the most pressing medical riddle of their time. In a triumph of multidisciplinary thinking, Johnson illuminates the intertwined histories of the spread of disease, the rise of cities, and the nature of scientific inquiry, offering both a riveting history and a powerful explanation of how it has shaped the world we live in.

Author Steven Johnson
Isbn 1101158530
Genre Science
Year 2006-10-19
Pages 320
Language English
File format PDF

Explore the facts, myths, science, history, and more behind infectious diseases from around the world with this ultimate trivia collection that will have you equally freaked out and fascinated. Taking a friendly approach to a serious subject, The Big Book of Infectious Disease Trivia answers all of your questions about pandemics, epidemics, and diseases—plus, it covers all of the bizarre questions you never thought to ask! From familiar diseases like influenza to ancient diseases like leprosy to oddly named diseases like mad cow disease, this trivia book tackles the mind-blowing facts and obscure details about many infectious diseases—past, present, and future. Get ready to broaden your understanding of humanity’s many illnesses, from survivable to deadly, with answers to questions like: What is the difference between an epidemic and a pandemic? What is the oldest known infectious disease? How is COVID-19 different from the flu and pneumonia? Who invented the face mask? What is herd immunity? What does it take to have an infectious disease declared “eradicated"? And more! With historical facts along with pop culture references, The Big Book of Infectious Disease Trivia is a must-have for anyone fascinated by infectious diseases.

Author Kristina Wright
Isbn 1646041399
Genre Medical
Year 2021-01-26
Pages 280
Language English
File format PDF

With a New Chapter and Updated Epilogue on Coronavirus A Financial Times Best Health Book of 2019 and a New York Times Book Review Editors’ Choice "Honigsbaum does a superb job covering a century’s worth of pandemics and the fears they invariably unleash." —Howard Markel, MD, PhD, director of the Center for the History of Medicine, University of Michigan How can we understand the COVID-19 pandemic? Ever since the 1918 Spanish influenza pandemic, scientists have dreamed of preventing such catastrophic outbreaks of infectious disease. Yet despite a century of medical progress, viral and bacterial disasters continue to take us by surprise, inciting panic and dominating news cycles. In The Pandemic Century, a lively account of scares both infamous and less known, medical historian Mark Honigsbaum combines reportage with the history of science and medical sociology to artfully reconstruct epidemiological mysteries and the ecology of infectious diseases. We meet dedicated disease detectives, obstructive or incompetent public health officials, and brilliant scientists often blinded by their own knowledge of bacteria and viruses—and see how fear of disease often exacerbates racial, religious, and ethnic tensions. Now updated with a new chapter and epilogue.

Author Mark Honigsbaum
Isbn 0393254763
Genre Medical
Year 2019-04-09
Pages 512
Language English
File format PDF

The novel coronavirus SARS-CoV-2, which causes the disease known as COVID-19, has infected people in 212 countries so far and on every continent except Antarctica. Vast changes to our home lives, social interactions, government functioning and relations between countries have swept the world in a few months and are difficult to hold in one’s mind at one time. That is why a collaborative effort such as this edited, multidisciplinary collection is needed. This book confronts the vulnerabilities and interconnectedness made visible by the pandemic and its consequences, along with the legal, ethical and policy responses. These include vulnerabilities for people who have been harmed or will be harmed by the virus directly and those harmed by measures taken to slow its relentless march; vulnerabilities exposed in our institutions, governance and legal structures; and vulnerabilities in other countries and at the global level where persistent injustices harm us all. Hopefully, COVID-19 will forces us to deeply reflect on how we govern and our policy priorities; to focus preparedness, precaution, and recovery to include all, not just some. Published in English with some chapters in French.

Author Colleen M. Flood,Vanessa MacDonnell,Jane Philpott,Sophie Thériault,Sridhar Venkatapuram
Isbn 077663643X
Genre Social Science
Year 2020-07-14
Pages 648
Language English
File format PDF

When it comes to Mars, the focus is often on how to get there: the rockets, the engines, the fuel. But upon arrival, what will it actually be like? In 2013, Kate Greene moved to Mars. That is, along with five fellow crew members, she embarked on NASA’s first HI-SEAS mission, a simulated Martian environment located on the slopes of Mauna Loa in Hawai'i. For four months she lived, worked, and slept in an isolated geodesic dome, conducting a sleep study on her crew mates and gaining incredible insight into human behavior in tight quarters, as well as the nature of boredom, dreams, and isolation that arise amidst the promise of scientific progress and glory. In Once Upon a Time I Lived on Mars, Greene draws on her experience to contemplate humanity’s broader impulse to explore. The result is a twined story of space and life, of the standard, able-bodied astronaut and Greene’s brother’s disability, of the lag time of interplanetary correspondences and the challenges of a long-distance marriage, of freeze-dried egg powder and fresh pineapple, of departure and return. By asking what kind of wisdom humanity might take to Mars and elsewhere in the Universe, Greene has written a remarkable, wide-ranging examination of our time in space right now, as a pre-Mars species, poised on the edge, readying for launch.

Author Kate Greene
Isbn 1250159482
Genre Science
Year 2020-07-14
Pages 256
Language English
File format PDF